Scholarly and Creative Works
2025
- Johnston, A., Olugbami, J. O., Walunj, D., Bangaru, A., Wu, B., Kern, R., … Oyelere, A. K. (2025). Transcriptomic Signature and PROTAC Strategy Revealed Histone Lysine Demethylase as a Target of Anticancer Activity of Deferiprone. https://doi.org/10.1101/2025.10.13.682199
2024
- Owumi, S., Olanlokun, J., Wu, B., Duro-Ladipo, A., Oyelere, S., Khan, S., & Oyelere, A. (2024). Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models. Molecules, 29(23), 5658. https://doi.org/10.3390/molecules29235658
- Wu, B., Tapadar, S., Ruan, Z., Sun, C. Q., Arnold, R. S., Johnston, A., … Oyelere, A. K. (2024). A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy. ACS Pharmacology & Translational Science, 7(10), 3155–3169. https://doi.org/10.1021/acsptsci.4c00358
2023
- Chandrasekaran, B., Tapadar, S., Wu, B., Saran, U., Tyagi, A., Johnston, A., … Damodaran, C. (2023). Antiandrogen-Equipped Histone Deacetylase Inhibitors Selectively Inhibit Androgen Receptor (AR) and AR-Splice Variant (AR-SV) in Castration-Resistant Prostate Cancer (CRPC). Cancers, 15(6), 1769. https://doi.org/10.3390/cancers15061769
2022
- Owumi, S. E., Kazeem, A. I., Wu, B., Ishokare, L. O., Arunsi, U. O., & Oyelere, A. K. (2022). Apigeninidin-rich Sorghum bicolor (L. Moench) extracts suppress A549 cells proliferation and ameliorate toxicity of aflatoxin B1-mediated liver and kidney derangement in rats. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-10926-1
- Guerra Faura, G., Wu, B., Oyelere, A. K., & France, S. (2022). Synthetic methodology-enabled discovery of a tunable indole template for COX-1 inhibition and anti-cancer activity. Bioorganic & Medicinal Chemistry, 57, 116633. https://doi.org/10.1016/j.bmc.2022.116633
- Wu, B., Sodji, Q. H., & Oyelere, A. K. (2022). Inflammation, Fibrosis and Cancer: Mechanisms, Therapeutic Options and Challenges. Cancers, 14(3), 552. https://doi.org/10.3390/cancers14030552
2020
- Tapadar, S., Fathi, S., Wu, B., Sun, C. Q., Raji, I., Moore, S. G., … Oyelere, A. K. (2020). Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents. Cancers, 12(11), 3095. https://doi.org/10.3390/cancers12113095
- Caggia, S., Tapadar, S., Wu, B., Venugopal, S. V., Garrett, A. S., Kumar, A., … Khan, S. A. (2020). Small Molecule Inhibitors Targeting Gαi2 Protein Attenuate Migration of Cancer Cells. Cancers, 12(6), 1631. https://doi.org/10.3390/cancers12061631
- Wu, B., Fathi, S., Mortley, S., Mohiuddin, M., Jang, Y. C., & Oyelere, A. K. (2020). Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity. Bioorganic & Medicinal Chemistry, 28(6), 115345. https://doi.org/10.1016/j.bmc.2020.115345
2019
- Crooke, S. N., Schimer, J., Raji, I., Wu, B., Oyelere, A. K., & Finn, M. G. (2019). Lung Tissue Delivery of Virus-Like Particles Mediated by Macrolide Antibiotics. Molecular Pharmaceutics, 16(7), 2947–2955. https://doi.org/10.1021/acs.molpharmaceut.9b00180