Faculty Profiles

Fang, Y., Su, Y., Meisel, R., Walters, J. R., Gamble, T., Randolph, E. C., … Duan, J. (Ellie). (2026). Comparative transcriptomic analysis of embryonic stem cells across mammalian species. iScience, 29(1), 114542. https://doi.org/10.1016/j.isci.2025.114542

Shi, M., Li, G., Araujo, H. M., Lee, A. S., Zhang, J., Lee, Y. L., … Duan, J. E. (2025). Sex-biased transcriptome in in vitro produced bovine early embryos. Cell & Bioscience, 15(1). https://doi.org/10.1186/s13578-025-01459-x

Biga, P. R., Duan, J. E., Young, T. E., Marks, J. R., Bronikowski, A., Decena, L. P., … Riddle, N. C. (2025). Hallmarks of aging: A user’s guide for comparative biologists. Ageing Research Reviews, 104, 102616. https://doi.org/10.1016/j.arr.2024.102616

Freij, K., Cleveland, B., & Biga, P. R. (2024). Remodeling of the epigenetic landscape in rainbow trout, Oncorhynchus mykiss, offspring in response to maternal choline intake. Comp Biochem Physiol Part D Genomics Proteomics ., 52. https://doi.org/10.1016/j.cbd.2024.101348

Reid, R. M., Turkmen, S., Cleveland, B. M., & Biga, P. R. (2024). Direct actions of growth hormone in rainbow trout, Oncorhynchus mykiss, skeletal muscle cells in vitro. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 297, 111725. https://doi.org/10.1016/j.cbpa.2024.111725

Freij, K., Cleveland, B., & Biga, P. R. (2024). Maternal dietary choline levels cause transcriptome shift due to genotype-by-diet interactions in rainbow trout (Oncorhynchus mykiss). Comp Biochem Physiol Part D Genomics Proteomics ., 49. https://doi.org/10.1016/j.cbd.2024.101193

Riddle, N. C., Biga, P. R., Bronikowski, A. M., Walters, J. R., Wilkinson, G. S., Duan, J. E., … Webb, A. (2023). Comparative analysis of animal lifespan. GeroScience, 46(1), 171–181. https://doi.org/10.1007/s11357-023-00984-2

Hogg, D. W., Reid, A. L., Dodsworth, T. L., Chen, Y., Reid, R. M., Xu, M., … Lovejoy, D. A. (2022). Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1. Frontiers in Physiology, 13.

Bronikowski, A. M., Meisel, R. P., Biga, P. R., Walters, J. R., Mank, J. E., Larschan, E., … Riddle, N. C. (2022). Sex‐specific aging in animals: Perspective and future directions. Aging Cell, 21(2). https://doi.org/10.1111/acel.13542

Cleveland, B. M., Leeds, T. D., Picklo, M. J., Brentesen, C., Frost, J., & Biga, P. R. (2020). Supplementing rainbow trout (Oncorhynchus mykiss) broodstock diets with choline and methionine improves growth in offspring. Journal of the World Aquaculture Society, 51(1), 266–281. https://doi.org/10.1111/jwas.12634

Reid, R. M., Freij, K. W., Maples, J. C., & Biga, P. R. (2019). Teneurins and Teneurin C-Terminal Associated Peptide (TCAP) in Metabolism: What’s Known in Fish? Frontiers in Neuroscience, 13. https://doi.org/10.3389/fnins.2019.00177

Reid, R. M., D’Aquila, A. L., & Biga, P. R. (2018). The validation of a sensitive, non-toxic in vivo metabolic assay applicable across zebrafish life stages. Comparative Biochemistry and Physiology Part C: Toxicology Pharmacology, 208, 29–37. https://doi.org/10.1016/j.cbpc.2017.11.004

Latimer, M. N., Freij, K. W., Cleveland, B. M., & Biga, P. R. (2018). Physiological and Molecular Mechanisms of Methionine Restriction. Frontiers in Endocrinology, 9. https://doi.org/10.3389/fendo.2018.00217

Galt, N. J., Froehlich, J. M., McCormick, S. D., & Biga, P. R. (2018). A comparative evaluation of crowding stress on muscle HSP90 and myostatin expression in salmonids. Aquaculture, 483, 141–148. https://doi.org/10.1016/j.aquaculture.2017.10.019

Biga, P. R., Latimer, M. N., Froehlich, J. M., Gabillard, J.-C., & Seiliez, I. (2017). Distribution of H3K27me3, H3K9me3, and H3K4me3 along autophagy-related genes highly expressed in starved zebrafish myotubes. Biology Open. https://doi.org/10.1242/bio.029090

Biga, P. R. (2017). miR-210 expression is associated with methionine-induced differentiation of trout satellite cells. Journal of Experimental Biology. https://doi.org/10.1242/jeb.154484

Galt, N. J., McCormick, S. D., Froehlich, J. M., & Biga, P. R. (2016). A comparative examination of cortisol effects on muscle myostatin and HSP90 gene expression in salmonids. General and Comparative Endocrinology, 237, 19–26. https://doi.org/10.1016/j.ygcen.2016.07.019

Seiliez, I., Froehlich, J. M., Marandel, L., Gabillard, J.-C., & Biga, P. R. (2015). Evolutionary history and epigenetic regulation of the three paralogous pax7 genes in rainbow trout. Cell and Tissue Research, 359(3), 715–727. https://doi.org/10.1007/s00441-014-2060-0

David  Allison, B. ., Lisa  Antoine, H. ., Scott  Ballinger, W. ., Marcas  Bamman, M. ., Biga, P. R., Victor  Darley-Usmar, M. ., … Mickie  Powell, L. . (2014). Aging and energetics’ ‘Top 40’ future research opportunities 2010-2013. https://doi.org/10.12688/f1000research.5212.1

Galt, N. J., Froehlich, J. M., Remily, E. A., Romero, S. R., & Biga, P. R. (2014). The effects of exogenous cortisol on myostatin transcription in rainbow trout, Oncorhynchus mykiss. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 175, 57–63. https://doi.org/10.1016/j.cbpa.2014.05.015

Galt, N. J., Froehlich, J. M., Meyer, B. M., Barrows, F. T., & Biga, P. R. (2014). High-fat diet reduces local myostatin-1 paralog expression and alters skeletal muscle lipid content in rainbow trout, Oncorhynchus mykiss. Fish Physiology and Biochemistry, 40(3), 875–886. https://doi.org/10.1007/s10695-013-9893-4

Picha, M. E., Biga, P. R., Galt, N., McGinty, A. S., Gross, K., Hedgpeth, V. S., … Borski, R. J. (2014). Overcompensation of circulating and local insulin-like growth factor-1 during catch-up growth in hybrid striped bass ( Morone chrysops × Morone saxatilis ) following temperature and feeding manipulations. Aquaculture, 428–429, 174–183. https://doi.org/10.1016/j.aquaculture.2014.02.028

Froehlich, J. M., Seiliez, I., Gabillard, J.-C., & Biga, P. R. (2014). Preparation of Primary Myogenic Precursor Cell/Myoblast Cultures from Basal Vertebrate Lineages. Journal of Visualized Experiments, (86). https://doi.org/10.3791/51354

Gabillard, J.-C., Biga, P. R., Rescan, P.-Y., & Seiliez, I. (2013). Revisiting the paradigm of myostatin in vertebrates: Insights from fishes. General and Comparative Endocrinology, 194, 45–54. https://doi.org/10.1016/j.ygcen.2013.08.012

Biga, P. R., Froehlich, J. M., Greenlee, K. J., Galt, N. J., Meyer, B. M., & Christensen, D. J. (2013). Gelatinases impart susceptibility to high-fat diet-induced obesity in mice. The Journal of Nutritional Biochemistry, 24(8), 1462–1468. https://doi.org/10.1016/j.jnutbio.2012.12.005

Froehlich, J. M., Fowler, Z. G., Galt, N. J., Smith Jr., D. L., & Biga, P. R. (2013). Sarcopenia and piscines: the case for indeterminate-growing fish as unique genetic model organisms in aging and longevity research. Frontiers in Genetics, 4, 159. https://doi.org/10.3389/fgene.2013.00159

Froehlich, J. M., Galt, N. J., Charging, M. J., Meyer, B. M., & Biga, P. R. (2013). In vitro indeterminate teleost myogenesis appears to be dependent on Pax3. In Vitro Cellular & Developmental Biology - Animal, 49(5), 371–385. https://doi.org/10.1007/s11626-013-9616-2

Meyer, B. M., Froehlich, J. M., Galt, N. J., & Biga, P. R. (2013). Inbred strains of zebrafish exhibit variation in growth performance and myostatin expression following fasting. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 164(1), 1–9. https://doi.org/10.1016/j.cbpa.2012.10.004

Rosauer, D. R., Biga, P. R., Lindell, S. R., Binkowski, F. P., Shepherd, B. S., Palmquist, D. E., … Goetz, F. W. (2011). Development of yellow perch (Perca flavescens) broodstocks: Initial characterization of growth and quality traits following grow-out of different stocks. Aquaculture, 317(1–4), 58–66. https://doi.org/10.1016/j.aquaculture.2011.03.037

Lyons, J. A., Haring, J. S., & Biga, P. R. (2010). Myostatin Expression, Lymphocyte Population, and Potential Cytokine Production Correlate with Predisposition to High-Fat Diet Induced Obesity in Mice. PLoS ONE, 5(9), e12928. https://doi.org/10.1371/journal.pone.0012928

Biga, P. R., & Meyer, J. M. (2009). Growth hormone differentially regulates growth and growth-related gene expression in closely related fish species. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 154(4), 465–473. https://doi.org/10.1016/j.cbpa.2009.07.023

Biga, P. R., & Goetz, F. W. (2006). Zebrafish and giant danio as models for muscle growth: determinate vs. indeterminate growth as determined by morphometric analysis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 291(5), R1327-37. https://doi.org/10.1152/ajpregu.00905.2005

Biga, P. R., Roberts, S. B., Iliev, D. B., McCauley, L. A. R., Moon, J. S., Collodi, P., & Goetz, F. W. (2005). The isolation, characterization, and expression of a novel GDF11 gene and a second myostatin form in zebrafish, Danio rerio. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 141(2), 218–230. https://doi.org/10.1016/j.cbpc.2005.03.004

Biga, P. R., Cain, K. D., Hardy, R. W., Schelling, G. T., Overturf, K., Roberts, S. B., … Ott, T. L. (2004). Growth hormone differentially regulates muscle myostatin1 and -2 and increases circulating cortisol in rainbow trout (Oncorhynchus mykiss). General and Comparative Endocrinology, 138(1), 32–41. https://doi.org/10.1016/j.ygcen.2004.05.001

Biga, P. R., Schelling, G. T., Hardy, R. W., Cain, K. D., Overturf, K., & Ott, T. L. (2004). The effects of recombinant bovine somatotropin (rbST) on tissue IGF-I, IGF-I receptor, and GH mRNA levels in rainbow trout, Oncorhynchus mykiss. General and Comparative Endocrinology, 135(3), 324–333. https://doi.org/10.1016/j.ygcen.2003.10.014