Biography and expertise
Dr Shen is an Assistant Professor in the Department of Mathematics at Texas State University. He earned his PhD in Statistics from Michigan State University and worked as a postdoctoral associate in the Department of Biostatistics at the University of Florida. His research sits at the intersection of statistical/machine learning theory and statistical genetics, focusing on neural-network- and kernel-based methods for genetic risk prediction and association analysis.
Education
Doctorate Degree
PhD in Statistics
Michigan State University, 2019
Master's Degree
MS in Statistics
Michigan State University, 2014
Bachelor's Degree
BS in Mathematics and Applied Mathematics
Shanghai University, 2012
Teaching Interests
Research Interests
Featured grants
- Zhu, Jie (Principal), Meireles, Christiane (Co-Principal), Shen, Xiaoxi (Supporting), Du, Yan (Supporting). Diet, Genetic risk, and Physical Activity in Association with Risk of Diabetes, Lone Star Collaborative Health Research Pilot Award, Institutional (Higher Ed), $100000. (Funded: August 30, 2027). Grant.
- Zhu, Jie (Principal), Shen, Xiaoxi (Co-Principal), Wang, Kaipeng (Co-Principal). Pork intake, Genetic Susceptibility, and Social Determinants in Association with Risk of Diabetes among a Population-based Prospective Study of US Hispanics/Latinos, National Pork Board, Private / Foundation / Corporate, $55000. (Submitted: April 23, 2025, Funded: September 1, 2025 - Present). Grant.
- Yang, Yong (Principal), Keller, Thomas M (Co-Principal), Sun, Shuying (Supporting), Dochtermann, Anton (Supporting), Oh, Suho (Supporting), Shen, Xiaoxi (Supporting), Xiao, Jun (Supporting). NSF REU Site: Algebra, Combinatorics, and Statistics (#: 2447229), NSF, Federal, $271568. (Submitted: August 2024, Funded: April 1, 2025 - March 28, 2028). Grant.
- Zhu, Jie (Principal), Shen, Xiaoxi (Co-Principal), Metsis, Vangelis (Co-Principal). One-carbon Metabolism Nutrients Intakes, Genetic Susceptibility, and Social Determinants in Association with Diabetes Incidence among the U.S. Hispanic Adults: HCHS/SOL, TXST CADS 2024 Catalyst Research Awards, Texas State Center for Analytics and Data Science, Texas State University, $1000. (Submitted: December 22, 2024, Funded: February 1, 2024 - December 31, 2024). Grant.
- Shen, Xiaoxi. Risk Prediction and Association Analyses Using Kernel Methods for High-Dimensional Genetic Data, Research Enhancement Program, Texas State University, $8000. (Funded: January 1, 2024 - May 31, 2025). Grant.

Featured scholarly/creative works
- Shen, X., & Lu, Q. (2025). Consistency of Restricted Maximum Likelihood Estimators in High-Dimensional Kernel Linear Mixed Effects Models with Applications to Estimating Genetic Heritability. Mathematics.
- Shen, X., & Espinoza, J. (2025). Consistency and Rate of Convergence for Deep ReLU Neural Networks. Journal of Statistical Theory and Practice.
- Sakia, G., Shen, X., Liu, Y., Yang, K., Wu, H., Lingpeng Lu, L., … Zhu, J. (2025). Associations of serum choline, betaine and trimethylamine N-oxide with gestational diabetes mellitus among Chinese pregnant women. BMJ Nutrition, Prevention, & Health, 8(1):e001111. https://doi.org/Impact factor(2024): 3.3
- Zhu, J., Saikia, G., Zhang, X., Shen, X., & Kahe, K. (2024). One-carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus. DIABETES METAB J, 48(2):170-183. https://doi.org/doi:%2010.4093/dmj.2023.0272. Impact factor(2024): 6.8
- Shen, X., Jiang, C., Sakhanenko, L., & Lu, Q. (2023). Asymptotic Properties of Neural Network Sieve Estimators. Journal of Nonparametric Statistics. https://doi.org/10.1080/10485252.2023.2209218
Featured awards
- Award / Honor Recipient: New Faculty Collection Grant Funds, $1011.25. October 2021
- Award / Honor Nominee: 2026 Department of Mathematics Service Excellence Award. October 4, 2026 - Present
- Award / Honor Nominee: 2026 Department of Mathematics Teaching Excellence Award. October 4, 2026 - Present
- Award / Honor Recipient: 2022 Outstanding Review Editor, Editorial Office of Frontiers in Systems Biology. October 3, 2022 - Present
- Award / Honor Nominee: College of Science and Engineering Research Excellence Award. February 1, 2025 - March 5, 2025

Featured service activities
- Reviewer / Referee
Statistics and Probability Letters
- Co-Chair
Machine Learning Reading Seminar
- Other
Mentor for Dr. Myungsoo Yoo
- Member
Data Science Program Abet Accreditation
- Member
Round Rock Data Science Program Planning Group
- Other
Teaching Mentor for Taylor Soliz
