Faculty Profiles

Colleges and Departments
Portrait of Dr. Ryan Loren Peterson

Dr. Ryan Loren Peterson

  • Assistant Professor at Chemistry and Biochemistry, College of Science & Engineering

Scholarly and Creative Works

2024

  • Anne, S., Friudenberg, A. F., & Peterson, R. L. (2024). Characterization of a High-Affinity Copper Transporter CTR1a in the White-Nose Syndrome Causing Fungal Pathogen Pseudogymnoascus destructans. Journal of Fungi. https://doi.org/https://doi.org/10.3390/jof10100729

2023

  • Igareta, N. V., Tachibana, R., Spiess, D., Peterson, R. L., & Ward, T. (2023). Shielding the active site: a streptavidin superoxidedismutase chimera as a host protein for asymmetric transfer hydrogenation. Faraday Discussions. https://doi.org/10.1039/d3fd00034f
  • Ogunwa, T., Thornhill, G., Ledezma, D., & Peterson, R. L. (n.d.). Modulation of Saprolegina parasitica growth using copper and ionophores.
  • Peterson, R. L., Ogunwa, T., Ledezma, D., & Thornhill, G. (2023). Boosting copper toxicity towards Saprolegina parasitica.

2021

  • Christoffel, F., Igareta, N. V., Pellizzoni, M. M., Tiessler-Sala, L., Lozhkin, B., Spiess, D. C., … Ward, T. R. (2021). Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis. Nature Catalysis, 4(8), 643–653. https://doi.org/10.1038/s41929-021-00651-9

2020

  • Schatzman, S. S., Peterson, R. L., Teka, M., He, B., Cabelli, D. E., Cormack, B. P., & Culotta, V. C. (2020). Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens. Journal of Biological Chemistry, 295(2), 570--583.
  • Serrano-Plana, J., Rumo, C., Rebelein, J. G., Peterson, R. L., Barnet, M., & Ward, T. R. (2020). Enantioselective Hydroxylation of Benzylic C(sp3)–H Bonds by an Artificial Iron Hydroxylase Based on the Biotin–Streptavidin Technology. Journal of the American Chemical Society, 142(24), 10617–10623. https://doi.org/10.1021/jacs.0c02788
  • Peterson, R. L. (2020). Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens. Journal of Biological Chemistry, 570–583. https://doi.org/10.1074/jbc.RA119.011084
  • Schatzman, S. S., Peterson, R. L., Teka, M., He, B., Cabelli, D. E., Cormack, B. P., & Culotta, V. C. (2020). Copper-only superoxide dismutase enzymes and iron starvation stress in Candida fungal pathogens. The Journal of Biological Chemistry, 295(2), 570–583. https://doi.org/10.1074/jbc.RA119.011084

2019

  • Liang, A. D., Serrano-Plana, J., Peterson, R. L., & Ward, T. R. (2019). Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology: Enzymatic Cascades and Directed Evolution. Accounts of Chemical Research, 52(3), 585–595. https://doi.org/10.1021/acs.accounts.8b00618

2018

  • Peterson, R. L., Robinett, N. G., & Culotta, V. C. (2018). Eukaryotic Cu-only Superoxide Dismutases (SODs): A new class of SOD enzymes and SOD-like protein domains. J. Biol. Chem, 4636–4643. Retrieved from http://www.jbc.org/site/thematics/metals_copper/

2017

  • Peterson, R. L., Garcia-Bosch, I., Cowley, R. E., Díaz, D. E., Solomon, E. I., & Karlin, K. D. (2017). Substrate and Lewis  Acid Coordination Promote O–O Bond Cleavage of an Unreactive L2CuII2(O22–) Species to Form L2CuIII2(O)2 Cores with Enhanced Oxidative Reactivity. J. Am. Chem. Soc., 3186–3195.
  • Schatzman, S., Teka, M., Peterson, R. L., Cabelli, D., & Culotta, V. (2017). The Irony of Cu-only Superoxide Dismutases in Fungal Pathogens. Free Radical Biology and Medicine, 112, 33.

2016

  • Peterson, R. L., Galaleldeen, A., Villarreal, J., Taylor, A. B., Cabelli, D. E., Hart, P. J., & Culotta, V. C. (2016). The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases. The Journal of Biological Chemistry, 291(40), 20911–20923. https://doi.org/10.1074/jbc.M116.748251

2015

  • Peterson, R. L., Ginsbach, K. S., Lee, J. W., Siegler, J. J., Sarjeant, M. A., & Solomon, A. A. (2015). Amine Oxidative N-Dealkylation via Cupric Hydroperoxide Cu-OOH Homolytic Cleavage Followed by Site-Specific Fenton Chemistry. J. Am. Chem. Soc., 137, 2867–2874.
  • Garcia-Bosch, I., Adam, S. M., Schaefer, A. W., Sharma, S. K., Peterson, R. L., Solomon, E. I., & Karlin, K. D. (2015). A “naked” Fe(III)-(O₂2−)-Cu(II) species allows for structural and spectroscopic tuning of low-spin heme-peroxo-Cu complexes. Journal of the American Chemical Society, 137(3), 1032–1035. https://doi.org/10.1021/ja5115198

2014

  • Lee, J. Y., Peterson, R. L., Ohkubo, K., Garcia-Bosch, I., Himes, R. A., Woertink, J., … Karlin, K. D. (2014). Mechanistic insights into the oxidation of substituted phenols via hydrogen atom abstraction by a cupric--superoxo complex. Journal of the American Chemical Society, 136(28), 9925--9937.
  • Lee, J. Y., Peterson, R. L., Ohkubo, K., Garcia-Bosch, I., Himes, R. A., Woertink, J., … Karlin, K. D. (2014). Mechanistic insights into the oxidation of substituted phenols via hydrogen atom abstraction by a cupric-superoxo complex. Journal of the American Chemical Society, 136(28), 9925–9937. https://doi.org/10.1021/ja503105b
  • Gleason, J. E., Galaleldeen, A., Peterson, R. L., Taylor, A. B., Holloway, S. P., Waninger-Saroni, J., … Culotta, V. C. (2014). Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense. Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5866–5871. https://doi.org/10.1073/pnas.1400137111

2013

  • Peterson, R. L., Ginsbach, J. W., Cowley, R. E., Qayyum, M. F., Himes, R. A., Siegler, M. A., … Karlin, K. D. (2013). Stepwise protonation and electron-transfer reduction of a primary copper-dioxygen adduct. Journal of the American Chemical Society, 135(44), 16454–16467. https://doi.org/10.1021/ja4065377
  • Peterson, R., Kim, S., & Karlin, K. (2013). Copper Enzymes.
  • Ginsbach, J. W., Peterson, R. L., Cowley, R. E., Karlin, K. D., & Solomon, E. I. (2013). Correlation of the electronic and geometric structures in mononuclear copper(II) superoxide complexes. Inorganic Chemistry, 52(22), 12872–12874. https://doi.org/10.1021/ic402357u
  • Kakuda, S., Peterson, R. L., Ohkubo, K., Karlin, K. D., & Fukuzumi, S. (2013). Enhanced catalytic four-electron dioxygen (O2) and two-electron hydrogen peroxide (H2O2) reduction with a copper(II) complex possessing a pendant ligand pivalamido group. Journal of the American Chemical Society, 135(17), 6513–6522. https://doi.org/10.1021/ja3125977

2011

  • Peterson, R. L., Himes, R. A., Kotani, H., Suenobu, T., Tian, L., Siegler, M. A., … Karlin, K. D. (2011). Cupric superoxo-mediated intermolecular C-H activation chemistry. Journal of the American Chemical Society, 133(6), 1702–1705. https://doi.org/10.1021/ja110466q

2010

  • Fukuzumi, S., Kotani, H., Lucas, H. R., Doi, K., Suenobu, T., Peterson, R. L., & Karlin, K. D. (2010). Mononuclear copper complex-catalyzed four-electron reduction of oxygen. Journal of the American Chemical Society, 132(20), 6874–6875. https://doi.org/10.1021/ja100538x

2008

  • Peterson, R. L., Banker, K. J., Garcia, T. Y., & Works, C. F. (2008). Isolation of a novel chromium(III) binding protein from bovine liver tissue after chromium(VI) exposure. Journal of Inorganic Biochemistry, 102(4), 833–841. https://doi.org/10.1016/j.jinorgbio.2007.12.003