Faculty Profiles

Colleges and Departments
Portrait of Professor Sean Michael Kerwin

Professor Sean Michael Kerwin

  • Regents' Professor at Chemistry and Biochemistry, College of Science & Engineering
  • Professor at Mtrls Sci, Engrg & Comrclzatn Prgm

Grants

2025

  • Kerwin, Sean Michael (Principal). Circular Dichroism Spectrometer, NIH, Federal, $209852. (Submitted: 2024, Funded: August 1, 2025 - 2027). Grant.

2024

  • Hudnall, Todd W (Principal), Kerwin, Sean Michael (Co-Principal), Peterson, Ryan Loren (Co-Principal), Shi, Xijun (Co-Principal), Schilter, David (Co-Principal), Haque, Ariful (Supporting), Droopad, Ravindranath (Supporting), Chen, Yihong (Supporting), Brittain, Bill (Supporting), Geerts, Wilhelmus J (Supporting), Kornienko, Alexander Vladimir (Supporting). MRI: Acquisition of a Single Crystal X-ray Diffractometer to Advance Structural Analysis in Chemical, Biochemical, and Material Sciences at Texas State University, National Science Foundation, Federal, $485000. (Submitted: November 15, 2023, Funded: August 15, 2024 - July 31, 2027). Grant.
  • Hudnall, Todd W (Principal), Kerwin, Sean Michael (Co-Principal), Schilter, David (Co-Principal), Peterson, Ryan Loren (Co-Principal), Shi, Xijun (Co-Principal). Equipment: MRI: Acquisition of a Single Crystal X-ray Diffractometer to Advance Structural Analysis in Chemical, Biochemical, and Material Sciences at Texas State University, National Science Foundation, Federal, $485000. (Funded: May 2024 - April 2025). Grant.

2022

  • Lewis, Karen A (Principal), Kerwin, Sean Michael (Co-Principal), Whitten, Steven T (Co-Principal), Kornienko, Alexander Vladimir (Supporting), Peterson, Ryan Loren (Supporting), Xue, Xiaoyu (Supporting). MRI: Acquisition of Automated Isothermal Titration Calorimeter for Biophysical Research at Texas State University, National Science Foundation, Federal, $262280. (Submitted: January 19, 2022, Funded: September 1, 2022 - August 31, 2025). Grant.
  • Lewis, Karen A (Principal), Luxford, Cynthia J (Co-Principal), Wheeler, Brittany Marie (Co-Principal), Webre, Whitney Ann (Co-Principal), Holland, Cory Lee (Co-Principal), Betancourt, Tania (Supporting), Brittain, William J (Supporting), Hudnall, Todd W (Supporting), Irvin, Jennifer A (Supporting), Kerwin, Sean Michael (Supporting), Kornienko, Alexander Vladimir (Supporting), Peterson, Ryan Loren (Supporting), Rhodes, Christopher Peter (Supporting). REU Site: A Chemistry REU on Molecular Innovation and Exploration (CheMIE), National Science Foundation, Federal, $378188. (Submitted: August 25, 2021, Funded: April 15, 2022 - Present). Grant.
  • Rhodes, Christopher Peter (Principal), Martin, Benjamin (Co-Principal), Schilter, David (Co-Principal), Kerwin, Sean Michael (Co-Principal), Kornienko, Alexander Vladimir (Co-Principal), Peterson, Ryan Loren (Co-Principal), Schwartz, Benjamin F (Co-Principal), Dutton, Jessica (Co-Principal), Ikehata, Keisuke (Co-Principal), Hwang, Sangchul Scott (Co-Principal), Ozbakkaloglu, Togay (Co-Principal). Inductively Coupled Plasma-Mass Spectrometry Shared Research and Education Instrument, Texas State University, $259195. (Funded: 2022 - 2023). Grant.

2021

  • Betancourt, Tania (Principal), Brittain, William J (Co-Principal), Irvin, Jennifer A (Co-Principal), Theodoropoulou, Nikoleta (Co-Principal), Martin, Benjamin (Co-Principal), Rhodes, Christopher Peter (Co-Principal), Wistey, Mark A (Co-Principal), Miyahara, Yoichi (Co-Principal), Kerwin, Sean Michael (Co-Principal). TxState-UT PREM Center for Intelligent Materials Assembly (CIMA), National Science Foundation, Federal, $3822000. (Funded: July 1, 2021 - June 30, 2027). Grant.
  • Lewis, Karen A (Principal), Kerwin, Sean Michael (Co-Principal), McLean, Robert J C (Co-Principal), Chang, Carolyn T (Supporting), David, Wendi M (Supporting). U-RISE at Texas State, National Institutes of Health - National Institute of General Medical Sciences, Federal, $2238578. (Funded: April 1, 2021 - March 31, 2026). Grant.

2017

  • Benavides, Elizabeth Ashley (Principal), Percent Contribution: %60, Mix, Kenneth D (Co-Principal), Percent Contribution: %20, Kerwin, Sean Michael (Co-Principal), Percent Contribution: %10, Rohde, Rodney E (Co-Principal), Percent Contribution: %10. Development of Novel anthelmintics and antiparasitics derived from plant sources, Institutional (Higher Ed), $30000. (Submitted: May 2017, Funded: August 1, 2017 - August 1, 2018). Grant.

2016

  • Kerwin, Sean Michael (Principal). Chemo-preventive Approach to Cancer Exploiting a Presumptive Link between Genomic Instability and Structural Stability of non-B DNA Sequences, CPRIT, State, $200000. (Funded: January 1, 2016 - December 31, 2017). Grant.
  • Kerwin, Sean Michael (Principal). Hypoxis-derived treatment for advanced lung cancer, Texas State University REP., Texas State University, $8000. (Funded: January 1, 2016 - May 31, 2017). Grant.
  • Kerwin, Sean Michael (Principal). Hypoxis-derived treatment for advanced lung cancer, Owens Foundation, Private / Foundation / Corporate, $147328. (Funded: January 1, 2016 - December 31, 2016). Grant.

2012

  • Calin, George (Principal), Kerwin, Sean Michael (Co-Principal). Development of G-quadruplex Ligands, TI3D, State, $100000. (Funded: November 1, 2012 - October 31, 2014). Grant.
  • Kerwin, Sean Michael (Principal). Rearrangements of Alkynylazoles, Welch Foundation, Private / Foundation / Corporate, $240000. (Funded: May 1, 2012 - April 30, 2016). Grant.

2010

  • Kerwin, Sean Michael (Principal). Rearrangements of Alkynylazoles, Welch Foundation, Private / Foundation / Corporate, $100000. (Funded: May 1, 2010 - April 30, 2012). Grant.

2008

  • Aggarwal, Bharat (Principal), Kerwin, Sean Michael (Co-Principal). Caffeic Acid-Based Specific Inhibitors of NF-kB, TI3D, State, $100000. (Funded: November 1, 2008 - June 30, 2009). Grant.

2007

  • Kerwin, Sean Michael (Principal). Molecular Recognition and DNA Damage, Welch Foundation, Private / Foundation / Corporate, $150000. (Funded: June 1, 2007 - May 31, 2010). Grant.

2006

  • Kerwin, Sean Michael (Principal). Kinase Binding-Induced Cyclizations: Selective Irreversible Inhibition of Kinases for the Treatment of Cancer, ATP/ARP, Federal, $99400. (Funded: May 15, 2006 - November 30, 2009). Grant.

2005

  • El Diwani, Hoda (Principal), Kerwin, Sean Michael (Co-Principal). Synthesis of Benzoxazole Derivatives with Potential Antitumor and Antiviral Activity, USDA, Federal, $100000. (Funded: August 1, 2005 - January 30, 2009). Grant.

2003

  • Robertus, Jon (Principal), Kerwin, Sean Michael (Co-Principal). Structure-Based Design of Ricin and Shiga Toxin Inhibitors, DoD, Federal, $687951. (Funded: August 1, 2003 - December 30, 2007). Grant.
  • Brodbelt, Jennifer (Principal), Kerwin, Sean Michael (Co-Principal). Design of DNA Interactive Agents and Characterization of Drug/DNA Complexes by ESI/MS, NIH, Federal, $347500. (Funded: May 1, 2003 - April 30, 2008). Grant.
  • Kerwin, Sean Michael (Principal). Pharmacy Student Research Training Program, Houston Foundation, Private / Foundation / Corporate, $50000. (Funded: January 1, 2003 - January 1, 2007). Grant.

2001

  • Kerwin, Sean Michael (Principal). Molecular Recognition and DNA Damage, Welch Foundation, Private / Foundation / Corporate, $150000. (Funded: June 1, 2001 - May 31, 2004). Grant.
  • Kerwin, Sean Michael (Principal). Drugs Based on the Aza-Bergman Cyclization Route to Diradicals, Foundation for Research, Private / Foundation / Corporate, $125000. (Funded: January 1, 2001 - December 31, 2001). Grant.

1999

  • Kerwin, Sean Michael (Principal). Cycloaromatization Chemistry of Alkynyl Imines, ACS-PRF, Private / Foundation / Corporate, $60000. (Funded: April 1, 1999 - August 31, 2002). Grant.

1998

  • Kerwin, Sean Michael (Principal). Molecular Recognition and DNA Damage, Welch Foundation, Private / Foundation / Corporate, $126000. (Funded: June 1, 1998 - May 31, 2000). Grant.

1995

  • Kerwin, Sean Michael (Other), Von Hoff, Daniel D (Co-Principal). Telomere and Telomerase Interactive Agents, NIH, Federal, $1302067. (Funded: September 26, 1995 - September 27, 2001). Grant.
  • Hoffman, David (Principal), Kerwin, Sean Michael (Co-Principal). Structure-Based Design Against Viral RNA Targets, ATP/ARP, Federal, $172385. (Funded: July 1, 1995 - June 30, 2000). Grant.
  • Kerwin, Sean Michael (Principal). Bis(propargylic) Sulfone- and Enediyne-Containing Crown Ethers, Welch Foundation, Private / Foundation / Corporate, $110000. (Funded: June 1, 1995 - May 31, 1998). Grant.

1994

  • Kerwin, Sean Michael (Principal). The Aza-Bergman Route to 2,5-Didehydropyridine, ACS-PRF, Private / Foundation / Corporate, $20000. (Funded: September 1, 1994 - December 31, 1996). Grant.
  • Kerwin, Sean Michael (Principal). Shape Selective DNA Minor Groove Ligands, NIH, Federal, $349879. (Funded: April 1, 1994 - March 31, 1998). Grant.

1991

  • Kerwin, Sean Michael (Principal). Synthesis and Reactions of Enediyne-Containing Crown Ethers, AACP, Institutional (Higher Ed), $50000. (Funded: November 1, 1991 - October 31, 1993). Grant.