Faculty Profiles

Wilson, C., Lewis, K. A., Fitzkee, N. C., Hough, L. E., & Whitten, S. T. (2023). ParSe 2.0: A web tool to identify drivers of protein phase separation at the proteome level. Protein Science, 32(9). https://doi.org/doi: 10.1002/pro.4756

Ibrahim, A. Y., Khaodeuanepheng, N. P., Amarasekara, D. L., Correia, J. J., Lewis, K. A., Fitzkee, N. C., … Whitten, S. T. (2023). Intrinsically disordered regions that drive phase separation form a robustly distinct protein class. Journal of Biological Chemistry, 299(1), 102801. https://doi.org/10.1016/j.jbc.2022.102801

Paiz, E. A., Lewis, K. A., & Whitten, S. T. (2021). Structural and energetic characterization of the denatured state from the perspectives of peptides, the coil library, and intrinsically disordered proteins. Molecules, 26(3). https://doi.org/10.3390/molecules26030634

Lewis, K. A., & Luxford, C. J. (2020). Integrating Manipulatives and Animations to Visualize Holliday Junctions. CourseSource, 7. https://doi.org/https://doi.org/10.24918/cs.2020.37

Roberts, J. E., & Lewis, K. A. (2020). Effect of the N‐terminal Region of Arabidopsis thaliana LARP6C in RNA Binding Specificity. In The FASEB Journal (1_supplement, Vol. 34, p. 631.49-631.49).

Norbury, B., & Lewis, K. A. (2020). The Structural and Functional Role of Vertebrate LARP6 N‐Terminal Region. In The FASEB Journal (1_supplement, Vol. 34).

Hackler, E. L., & Lewis, K. A. (2020). The Structural Characterization of AtLaRP6a C‐Terminal Domain. In The FASEB Journal (1_supplement, Vol. 34).

Dock-Bregeon, A.-C., Lewis, K. A., & Conte, M. R. (2019). Structural Advances in La and La Related Proteins. RNA Biology. https://doi.org/10.1080/15476286.2019.1695712

Zepeda, S. K., & Lewis, K. A. (2019). Mechanisms of Nuclear Export of the RNA-Binding Protein LARP6. In The FASEB Journal (1_supplement, Vol. 33, p. 631.49-631.49).

Ream, J. A., Lewis, L., & Lewis, K. A. (2018). Horizontal Agarose Gel Mobility Shift Assay for Protein-RNA Complexes. Methods in Molecular Biology, 1855, 363–370. https://doi.org/10.1007/978-1-4939-8793-1_31

Lewis, K. A., Altschuler, S. E., & Wuttke, D. S. (2018). Measuring Low-Picomolar Apparent Binding Affinities by Minigel Electrophoretic Mobility Shift. Methods in Molecular Biology, 1855, 341–354. https://doi.org/10.1007/978-1-4939-8793-1_29

Stephens, D., Wright, C., McIntosh, R., Lewis, K. A., & Garcia, D. M. (2018). Using molecular techniques to determine protein binding partners.

Stephens, D., Wright, C., Garcia, D. M., & Lewis, K. A. (2018). Detection of the zebrafish Mrp4 protein using a commercial antibody.

Foster, J. S., Foster, C. L., Otte-Petrill, C., Betancourt, F. C., Billey, E., Bousquet-Antonelli, C., & Lewis, K. A. (2018). Exploring the effect of conserved motifs on the structure and activity of the RNA-binding protein LARP6c from Arabidopsis thaliana. In The FASEB Journal (1_supplement, Vol. 32, p. 790.7-790.7).

Peña, E. L., Külköylüoglu, H., Castro, J. M., Pu, X., Warner, L. R., & Lewis, K. A. (2018). Identification of Major Boundaries for Structural Characterization of the LARP6 Proteins From Fish. In The FASEB Journal (1_supplement, Vol. 32, p. 790.10-790.10).

Toner, C. M., Chovanec, L., Foster, C. L., Foster, J. S., Otte-Petrill, C., Betancourt, F. C., … Lewis, K. A. (2018). A structural role for the C-terminal conserved LSA motifs in Arabidopsis LARP6 proteins. In The FASEB Journal (1_supplement, Vol. 32, p. 526.5-526.5).

Castro, J. M., Horn, D. A., Pu, X., & Lewis, K. A. (2017). Expression and Purification of LARP6 Homologs From Fish Genetic Model Organisms. Protein Expression and Purification, 134, 147–153.

Peña, E. L., Lane, L. F., Salas, E., Castro, J. M., & Lewis, K. A. (2017). Role of cystines in the structure and function of the RNA-binding protein LARP6. In The FASEB Journal (1_supplement, Vol. 31, p. 598.1-598.1).

Zepeda, S. K., Villarreal, M. A., Biediger, N. M., Bonner, N. A., Miller, J. N., Ricard, B. J., … Lewis, K. A. (2017). Determining Zebrafish Epitope Reactivity to Commercially Available Antibodies. In The FASEB Journal (1_supplement, Vol. 31, p. 912.2-912.2).

Toner, C. M., Betancourt, F. C., & Lewis, K. A. (2017). Effect of Histidine Rich Sequence Motifs on the RNA Binding Activity of LARP6. In The FASEB Journal (1_supplement, Vol. 31, p. 598.3-598.3).

Castro, J. M., Horn, D. A., & Lewis, K. A. (2017). Biochemical Characterization of Evolutionary Divergent Vertebrate LARP6 Proteins. In The FASEB Journal (1_supplement, Vol. 31, p. 598.4-598.4).

Villarreal, M. A., Biediger, N. E., Bonner, N. A., Miller, J. N., Zepeda, S. K., Ricard, B. J., … Lewis, K. A. (2017). Determining Zebrafish Epitope Reactivity to Commercially Available Antibodies. Zebrafish, 14(4), 387–389. https://doi.org/10.1016/j.pep.2017.04.004

Ream, J. A., Lewis, L. K., & Lewis, K. A. (2016). Rapid agarose gel electrophoretic mobility shift assay for quantitating protein:RNA interactions. Analytical Biochemistry, 511, 36–41. Retrieved from 10.1016/j.ab.2016.07.027

Castro, J. M., Salas, E., Peña, E. L., Kocian, A., & Lewis, K. A. (n.d.). Analysis of RNA Binding by Evolutionarily Divergent LARP6 Proteins. In The FASEB Journal (1_supplement, Vol. 30, p. 592.2-592.2).

Villarreal, M., Euhus, B., Ricard, B., Garcia, D. M., & Lewis, K. A. (2015). Validation of anti-human MT1 antibody binding in zebrafish, a model organism. San Marcos, Texas, USA: 20th Annual Biology Colloquium, Texas State University.

Lewis, K. A., Pfaff, D. A., Earley, J. N., Altschuler, S. E., & Wuttke, D. S. (2014). The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain. Nucleic Acids Research, 42(1), 475–485.

Altschuler, S. E., Lewis, K. A., & Wuttke, D. S. (2013). Practical Strategies for the Evaluation of High-Affinity Protein/Nucleic Acid Interactions. Journal of Nucleic Acids Investigation, 4(1), e3-. https://doi.org/10.4081/jnai.2013.e3

Lewis, K. A., & Wuttke, D. S. (2012). Telomerase and telomere-associated proteins: structural insights into mechanism and evolution. Structure, 20(1), 28–39.

Lewis, K. A., Yaeger, A., DeMartino, G. N., & Thomas, P. J. (2010). Accelerated Formation of Alpha Synuclein Oligomers by Concerted Action of the 20S Proteasome and Familial Parkinson’s Mutation. Journal of Bioenergetics and Biomembranes, 42(1), 85–95. https://doi.org/10.1007/s10863-009-9258-y

Lewis, K. A., Su, Y., Jou, O., Ritchie, C., Foong, C., Hynan, L. S., … Hatanpaa, K. J. (2010). Abnormal neurites containing C-terminally truncated ?-synuclein are present in Alzheimer’s Disease without conventional Lewy body pathology. American Journal of Pathology, 177(6), 3037–3050. https://doi.org/10.2353/ajpath.2010.100552

Chen, Z., Lewis, K. A., Shultzaberger, R. K., Lyakhov, I. G., Zheng, M., Doan, B., … Schneider, T. D. (2007). Discovery of Fur binding site clusters in Escherichia coli by information theory models. Nucleic Acids Research, 35(20), 6762–6777.

Shultzaberger, R. K., Chen, Z., Lewis, K. A., & Schneider, T. D. (2007). Anatomy of Escherichia coli sigma70 promoters. Nucleic Acids Research, 35(3), 771–788.

Liu, C., Giasson, B. I., Lewis, K. A., Lee, V. M., DeMartino, G. N., & Thomas, P. J. (2005). A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease. Journal of Biological Chemistry, 280(24), 22670–22678.

Zheng, M., Wang, X., Doan, B., Lewis, K. A., Schneider, T. D., & Storz, G. (2001). Computation-directed identification of OxyR DNA binding sites in Escherichia coli. Journal of Bacteriology, 183(15), 4571–4579. Retrieved from 10.1128/JB.183.15.4571-4579.2001