Faculty Profile for Dr. Alexander Vladimir Kornienko

profile photo for Dr. Alexander Vladimir Kornienko
Dr. Alexander Vladimir Kornienko
Professor — Chemistry and Biochemistry
CHEM 319
phone: (512) 245-3632

Biography Section

Biography and Education

Postdoctoral Fellowship, Université de Montréal, Canada (Prof. Stephen Hanessian), 1999–2001
Ph.D. in Chemistry, Tufts University, Boston, USA (Prof. Marc d’Alarcao) 1994–1999
B.S in Chemical Engineering, Mendeleev University, Moscow, Russia, 1989–1994

Research Interests

Synthetic Organic Chemistry (total synthesis and methodology)
Chemical Biology (focus on cancer signaling and death pathways)
Medicinal Chemistry (rational drug design and library screening)
Natural Product Chemistry (isolation, structure elucidation and analogue synthesis)

Selected Scholarly/Creative Work

  • Aksenov, N., Arutiunov, N., Aksenov, A., Kirilov, N., Aksenova, I., Aksenov, D., … Kornienko, A. V. (2023). Synthesis of β-Carbolines with Electrocyclic Cyclization of 3-Nitrovinylindoles. International Journal of Molecular Sciences, 24, 13107.
  • Arutiunov, N., Aksenov, A., Aksenov, D., Kurenkov, I., Aksenova, I., Zatsepilina, A., … Kornienko, A. V. (2023). Convenient synthesis of (Z)-3-(1-aryl-2-nitrovinyl)-indoles. Tetrahedron Letters, 129, 154722.
  • Bretin, L., Husiev, Y., Ramu, V., Zhang, L., Hakkennes, M., Abyar, S., … Bonnet, S. (2023). Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage. Angewandte Chemie International Edition English, e202316425.
  • Ranganathan, S., Kornienko, A. V., Evidente, A., Romo, D., & Taube, J. (2023). Triple negative breast cancer targeted by Ophiobolin A: Epithelial-mesenchymal transition take the lead. In Cancer Research (Vol. 83).
  • Bretin, L., Vadde, R., Zheng, S., Gerhard, S., Zander, S., Kornienko, A. V., & Bonnet, S. (2023). Testing ruthenium-based photoactivated chemotherapy on tumor-bearing mice models as a new treatment for uveal melanoma. In Photodiagnosis and Photodynamic Therapy (March, Vol. 41, p. 103403). ScienceDirect.

Selected Awards

  • Award / Honor Recipient: Holder of Denise M. Trauth Endowed Presidential Research Professorship, Texas State University. 2021 - Present
  • Award / Honor Recipient: Presidential Award for Scholarly/Creative Activities, President. January 31, 2016 - August 25, 2016

Selected Grants

  • Lewis, Karen A (Principal), Kerwin, Sean Michael (Co-Principal), Whitten, Steven T (Co-Principal), Kornienko, Alexander Vladimir (Supporting), Peterson, Ryan Loren (Supporting), Xue, Xiaoyu (Supporting). MRI: Acquisition of Automated Isothermal Titration Calorimeter for Biophysical Research at Texas State University, National Science Foundation, Federal, $262280. (Submitted: January 19, 2022, Funded: September 1, 2022 - August 31, 2025). Grant.
  • Lewis, Karen A (Principal), Luxford, Cynthia J (Co-Principal), Wheeler, Brittany Marie (Co-Principal), Webre, Whitney Ann (Co-Principal), Holland, Cory Lee (Co-Principal), Betancourt, Tania (Supporting), Brittain, William J (Supporting), Hudnall, Todd W (Supporting), Irvin, Jennifer A (Supporting), Kerwin, Sean Michael (Supporting), Kornienko, Alexander Vladimir (Supporting), Peterson, Ryan Loren (Supporting), Rhodes, Christopher Peter (Supporting). REU Site: A Chemistry REU on Molecular Innovation and Exploration (CheMIE), National Science Foundation, Federal, $378188. (Submitted: August 25, 2021, Funded: April 15, 2022 - Present). Grant.
  • Du, Liqin (Principal), Kornienko, Alexander (Other), Houhgton, Peter (Other). Discovery of new differentiation agents for neuroblastoma therapy, National Institute of Health, NCI, R15, resubmissiom, Federal, $461574. (Funded: August 1, 2017 - July 31, 2020). Grant.
  • Rhodes, Christopher Peter (Principal), Martin, Benjamin (Co-Principal), Schilter, David (Co-Principal), Kerwin, Sean Michael (Co-Principal), Kornienko, Alexander Vladimir (Co-Principal), Peterson, Ryan Loren (Co-Principal), Schwartz, Benjamin F (Co-Principal), Dutton, Jessica (Co-Principal), Ikehata, Keisuke (Co-Principal), Hwang, Sangchul Scott (Co-Principal), Ozbakkaloglu, Togay (Co-Principal). Inductively Coupled Plasma-Mass Spectrometry Shared Research and Education Instrument, Texas State University, $259195. (Funded: 2022 - 2023). Grant.
  • Kornienko, Alexander Vladimir (Co-Principal), Lane, Michelle A (Co-Principal). Evaluation of 7-deazahypoxanthine derivatives as cancer chemotherapeutic agents, ORSP Research Accelerator, Texas State University, $20000. (Submitted: February 2022, Funded: February 2022 - May 2023). Grant.

Selected Service Activities

College Review Committee
Personnel Committee
Editorial Review Board Member
Current Pharmaceutical Design
Editorial Review Board Member
Marine Drugs
August 28, 2019-Present
Departmental Safety Committee