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Dr. Alexander Vladimir Kornienko

  • Professor - Chemistry and Biochemistry
Portrait of Dr. Alexander Vladimir Kornienko

Biography and education

Postdoctoral Fellowship, Université de Montréal, Canada (Prof. Stephen Hanessian), 1999–2001
Ph.D. in Chemistry, Tufts University, Boston, USA (Prof. Marc d’Alarcao) 1994–1999
B.S in Chemical Engineering, Mendeleev University, Moscow, Russia, 1989–1994

Research Interests

  • Lewis, Karen A (Principal), Kerwin, Sean Michael (Co-Principal), Whitten, Steven T (Co-Principal), Kornienko, Alexander Vladimir (Supporting), Peterson, Ryan Loren (Supporting), Xue, Xiaoyu (Supporting). MRI: Acquisition of Automated Isothermal Titration Calorimeter for Biophysical Research at Texas State University, National Science Foundation, Federal, $262280. (Submitted: January 19, 2022, Funded: September 1, 2022 - August 31, 2025). Grant.
  • Lewis, Karen A (Principal), Luxford, Cynthia J (Co-Principal), Wheeler, Brittany Marie (Co-Principal), Webre, Whitney Ann (Co-Principal), Holland, Cory Lee (Co-Principal), Betancourt, Tania (Supporting), Brittain, William J (Supporting), Hudnall, Todd W (Supporting), Irvin, Jennifer A (Supporting), Kerwin, Sean Michael (Supporting), Kornienko, Alexander Vladimir (Supporting), Peterson, Ryan Loren (Supporting), Rhodes, Christopher Peter (Supporting). REU Site: A Chemistry REU on Molecular Innovation and Exploration (CheMIE), National Science Foundation, Federal, $378188. (Submitted: August 25, 2021, Funded: April 15, 2022 - Present). Grant.
  • Du, Liqin (Principal), Percent Contribution: %10, Kornienko, Alexander (Other), Percent Contribution: %5, Houhgton, Peter (Other), Percent Contribution: %1. Discovery of new differentiation agents for neuroblastoma therapy, National Institute of Health, NCI, R15, resubmissiom, Federal, $461574. (Funded: August 1, 2017 - July 31, 2020). Grant.
  • Kornienko, Alexander Vladimir (Co-Principal), Percent Contribution: %7, Romo, Daniel (Principal), Percent Contribution: %93. Pharmacophore-Directed Retrosynthesis Applied to Bioactive Natural Products Informing Mechanism of Action Studies, NIH, Federal, $2250000. (Submitted: January 2024, Funded: January 2025 - January 2030). Grant.
  • Hudnall, Todd W (Principal), Kerwin, Sean Michael (Co-Principal), Peterson, Ryan Loren (Co-Principal), Shi, Xijun (Co-Principal), Schilter, David (Co-Principal), Haque, Ariful (Supporting), Droopad, Ravindranath (Supporting), Chen, Yihong (Supporting), Brittain, Bill (Supporting), Geerts, Wilhelmus J (Supporting), Kornienko, Alexander Vladimir (Supporting). MRI: Acquisition of a Single Crystal X-ray Diffractometer to Advance Structural Analysis in Chemical, Biochemical, and Material Sciences at Texas State University, National Science Foundation, Federal, $485000. (Submitted: November 15, 2023, Funded: August 15, 2024 - July 31, 2027). Grant.
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  • Bretin, L., Husiev, Y., Ramu, V., Zhang, L., Hakkennes, M., Abyar, S., … Bonnet, S. (2024). Red-Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage. Angewandte Chemie International Edition English, e202316425.
  • Aksenov, D., Smith, J., Aksenov, A., Prityko, L., Aksenov, N., Kuzminov, I., … Kornienko, A. V. (2024). 2-(3-Indolyl)acetamides and their oxazoline analogues: Anticancer SAR study. Bioorganic and Medicinal Chemistry Letters, 102, 129681.
  • van der Westhuyzen, A., Ashraf, N., Conradie, D., Loots, L., Kaschula, C., Pelly, S., … van Otterlo, W. (2024). Improved rigidin-inspired antiproliferative agents with modifications on the 7-deazahypoxanthine C7/C8 ring systems. Journal of Medicinal Chemistry, 67, 9950–9975.
  • Maslivetc, V., Hasan, N., Boari, A., Zejnelovski, A., Evidente, A., Sun, D., & Kornienko, A. V. (2024). Ophiobolin A derivatives with enhanced activities under tumor-relevant acidic conditions. Bioorganic and Medicinal Chemistry Letters, 110, 129863.
  • Ingels, A., Scott, R., Hooper, A., van der Westhuyzen, A., Wagh, S., de Meester, J., … Mathieu, V. (2024). New hemisynthetic derivatives of sphaeropsidin phytotoxins triggering severe endoplasmic reticulum swelling in cancer cells. Scientific Reports, 14, 14674.
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  • Award / Honor Recipient: Holder of Denise M. Trauth Endowed Presidential Research Professorship, Texas State University. 2021 - 2024
  • Award / Honor Recipient: 2024 Presidential Distinction Award, Texas State University. August 2024
  • Award / Honor Recipient: Presidential Award for Scholarly/Creative Activities, President. January 31, 2016 - August 25, 2016
  1. Member

    IMBC Faculty Search Committe

  2. Member

    IMBC Admission Committee

  3. Member

    College Review Committee

  4. Chair

    Personnel Committee

  5. Member

    Graduate Admission Committee

  6. Editorial Review Board Member

    Current Pharmaceutical Design

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