Faculty Profiles

Colleges and Departments
Portrait of Dr. Wendi M David

Dr. Wendi M David

  • Professor of Instruction at Chemistry and Biochemistry, College of Science & Engineering

Scholarly and Creative Works

2024

  • Das, M. K., Williams, E. P., Myhre, M. W., David, W. M., & Kerwin, S. M. (2024). Calcium-Dependent Chemiluminescence Catalyzed by a Truncated c-MYC Promoter G-Triplex DNA. Molecules, 29, 4457. Retrieved from https://doi.org/10.3390/molecules29184457
  • Kerwin, S. M., David, W. M., Myhre, M. W., & Das, M. K. (2024). Investigations of G-Triplex DNA formation by Surface Plasmon Resonance. Journal of Biological Chemistry, 300(3), 106585. Retrieved from https://www.jbc.org/article/S0021-9258(24)01058-5/fulltext

2019

  • Kerwin, S. M., Long, K., & David, W. M. (2019). Non-Canonical DNA in the c-Myc Hotspot Region. FASEB Journal, 33(1S).
  • Al-Der, C. C., David, W. M., Tippayasak, K., Tuesuwan, B., & Kerwin, S. M. (2019). G-Triplex DNA Formation Determined by SPR and Native Agarose Gel Electrophoresis. FASEB Journal, 33(1S).
  • Kerwin, S. M., Bracey, H., Navapan, N., Tippayasak, K., Al-Der, C., Baqdounes, Y., … Tuesuwan, B. (2019). Spectroscopic, Gel Electrophoretic, and Surface Plasmon Resonance Characterization of G-Triplex DNA Formation. FASEB Journal, 32(1), 775.4.

2018

  • Kerwin, S. M., Long, K., & David, W. M. (2018). Non-Canonical DNA in the c-Myc Hotspot Region. Federation of American Societies for Experimental Biology Journal, 31(1), S522.1.

2015

  • Kerwin, S. M., & David, W. M. (2015). G-Quadruplex Dynamics:  Assays for Intramolecular G-Quadruplex Helicases and Inhibitors. In D. Monchaud (Ed.), Biological & Therapeutic Applications of DNA- and RNA-Quadruplexes (pp. 85–99). London: Future Science.
  • David, W. M., & Brittain, W. J. (2015). CheMIE REU chemistry research community with a focus on molecular innovation and entrepreneurship. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (Vol. 249).

2014

  • Gonzalez, A., Peltier, G., Booth, R., & David, W. (2014). Binding affinity of epithelial sodium channel subunits and peptides measured through surface plasmon resonance. FASEB J., 28.

2012

  • Perez, A. N., Oehlers, L., Heater, S. J., Booth, R. E., Walter, R. B., & David, W. M. (2012). Proteomic Analyses of the Xiphophorus Gordon-Kosswig Melanoma Model, 155, 81–88. https://doi.org/10.1016/j.cbpc.2011.05.017

2011

  • Decker, M., Mishra, B., Kumar, D., & David, W. M. (2011). Inhibition of G-Quadruplex Helicase Activity as Determined by Surface Plasmon Resonance. In R. D. Sheardy & S. A. Winkle (Eds.), Frontiers in Nucleic Acids (p. 1). Washington, DC: American Chemical Society. https://doi.org/10.1021/bk-2011-1082

2010

  • David, W. M. (2010). SPR-Facilitated Interrogation of Enzymatic Reactions Involving Nucleic Acids. In Plasmons: Theory and Applications. Hauppage, NY: Nova Publishers.
  • Plyler, J. R., Sanjar, F., Howard, R., Araki, N., & David, W. M. (2010). Optimization of Surface Plasmon Resonance Based Assay for Investigating T-antigen Helicase Activity J. Biotech. Res., 2, 56–66.
  • Laroche, C., Li, J., Gonzales, C., David, W. M., & Kerwin, S. M. (2010). Studies of Cyclization Kinetics and Biological Evaluation of an Anticancer 1,2-Dialkynylimidazole. Org. Biomol. Chem. Lett., 8, 1535–1539.
  • David, W. M., & Booth, R. E. (2010). Biochemical Laboratory Experiments Inspired by the 2004 Molecular Genetics and Protein Structure and Function Workshop. Abstracts of the 21st Biennial Conference on Chemical Education (BCCE), P436.
  • David, W. M., & Booth, R. E. (2010). Biochemical Laboratory Experiments Inspired by the 2004 Molecular Genetics and Protein Structure and Function Workshop. Abstracts of the 21st Biennial Conference on Chemical Education (BCCE).

2009

  • Jasheway, K., Plyler, J., Brennan, J. S., Karr, J., Kerwin, S. M., & David, W. M. (2009). Real-time Investigation of Simian Virus 40 Large T-antigen Helicase Activity by Surface Plasmon Resonance. Cell Biochem. Biophys, 53, 43–52.
  • Howard, R., Plyler, J. R., Williams, S., Araki, N., & David, W. M. (2009). Optimization of SPR-based assay for monitoring SV40 large T-antigen helicase activity. FASEB J., 23, 860.1.
  • Howard, R., Plyler, J. R., Williams, S., Araki, N., & David, W. M. (2009). Optimization of SPR-based assay for monitoring SV40 large T-antigen helicase activity. FASEB J, 23, 860.1.

2008

  • Cassidy, P., & David, W. M. (2008). Summary of Key Concepts for Organic Chemistry. Dubuque, IA: Kendall/Hunt.
  • Tuesuwan, B., Kern, J. T., Thomas, P. W., Rodriguez, M., Li, J., David, W. M., & Kerwin, S. M. (2008). Simian Virus 40 Large T-Antigen G-Quadruplex DNA Helicase Inhibition by G-Quadruplex DNA-Interactive Agents. Biochemistry, 47, 1896–1909.
  • David, W. M., Plyler, J., & Kerwin, S. M. (2008). Monitoring SV40 T-antigen Activity and Inhibition in Real Time Using Surface Plasmon Resonance. Book of Abstracts.
  • Brennan, J., Karr, J. R., Jasheway, K., & David, W. M. (2008). Characterization of  SV40 T-antigen G-quadruplex Helicase Activity Using SPR. FASEB J., 22.
  • David, W. M., Karr, J., Brennan, J., Jasheway, K., & Kerwin, S. M. (2008). Real-time Investigation of SV40 T-antigen Helicase Activity Using SPR. Book of Abstracts.

2006

  • Kerwin, S. M., Tuesuwan, B., Rodriguez, M., & David, W. M. (2006). SV-40 T-antigen Helicase Inhibition by G-Quadruplex Interactive Compounds. Book of Abstracts.

2004

  • Hennrich, G., David, W. M., Bomble, Y. J., Anslyn, E. V., Brodbelt, J. S., & Stanton, J. F. (2004). Self-assembling Dimeric and Trimeric Aggregates Based on Solvophobic and Charge-pairing Interactions. Supramolecular Chem., 16, 521–528.
  • David, W. M., Mitchell, D. L., & Walter, R. B. (2004). DNA Repair in Hybrid Fish of the Genus. Xiphophorus  Comp. Biochem. Physiol, 138, 300–310.
  • Oehlers, L. P., Heater, S. J., Rains, J. D., Wells, M. C., David, W. M., & Walter, R. B. (2004). Gene structure, Purification, and Characterization of DNA polymerase ß. Xiphophorus Maculates  Comp. Biochem. Physiol., 138, 311–324.

2003

  • David, W. M., & Brodbelt, J. S. (2003). Threshold Dissociation Energies of Protonated Amine/Polyether Complexes in a Quadrupole Ion Trap. J. Am. Soc. Mass Spectrom, 14, 383–392.

2002

  • Nadipuram, A. K., David, W. M., Kumar, D., & Kerwin, S. M. (2002). Synthesis and Thermolysis of Heterocyclic 3-Aza-3-ene-1,5-diynes. Organic Lett., 4, 4543–4546.
  • David, W. M., Brodbelt, J., Kerwin, S. M., & Thomas, P. W. (2002). Investigation of Quadruplex Oligonucleotide-Drug Interactions by Electrospray Ionization-Mass Spectrometry. Anal. Chem., 74, 2029–2033.
  • Tuntiwechapikul, W., David, W. M., Kumar, D., Salazar, M., & Kerwin, S. M. (2002). DNA Modification by 4-Aza-3-ene-1,6-diynes: DNA Cleavage, pH-Dependent Cytosine-Specific Interactions, and Cancer Cell Cytotoxicity. Biochemistry, 41, 5283–5290.
  • David, W. M., & Brodbelt, J. S. (2002). Abstracts of the 50th ASMS Conference on Mass Spectrometry and Allied TopicsAbstracts of the 50th ASMS Conference on Mass Spectrometry and Allied Topics. Abstracts of the 50th ASMS Conference on Mass Spectrometry and Allied Topics.
  • David, W. M., & Brodbelt, J. S. (2002). Relative Binding Energies of Hydrogen-Bonded Complexes. Abstracts of the 50th ASMS Conference on Mass Spectrometry and Allied Topics.

2001

  • Paquette, L. A., Ra, C. S., Galluci, J. C., Kang, H.-J., Ohmori, N., Arrington, M., … Brodbelt, J. (2001). Constraining of Small-Ring Cyclic Ether Triads by Stereodefined Spiroannulation to an Inositol Orthoformate Platform. Solution and Gas-Phase Alkali Metal Binding Affinities for 3- to 5-Membered Ring Structural Combinations. J. Org. Chem., 66, 8629–8639.
  • Kumar, D., David, W. M., & Kerwin, S. M. (2001). N-Propargyl-2-alkylbenzothiazolium Aza-enediynes: Role of the 2-alkylbenzothiazolium Functionality in DNA Cleavage. Bioorg. Med. Chem. Lett., 11, 2971–2974.

2000

  • David, W. M., Kumar, D., & Kerwin, S. M. (2000). Synthesis of a Heterocyclic Aza-enediyne and its DNA-cleavage Properties. Bioorg. Med. Chem. Lett., 10, 2509–2512.
  • David, W. M., & Kerwin, S. M. (2000). Heterocyclic Aza-variants of Enediynes: Potent DNA Cleavage Agents with Promising Antitumor Activity. Book of Abstracts.

1998

  • Kerwin, S. M., & David, W. M. (1998). C,N-Dialkynylimines as a Promising System for Generating Reactive Diradicals. Abstracts of the 8th Graduate Medicinal Chemistry Conference, 1.

1997

  • David, W. M., & Kerwin, S. M. (1997). Synthesis and Thermal Rearrangement of C, N,-Dialkynyl Imines: A Potential Aza-Bergman Route to 2,5-Didehydropyridine. J. Am. Chem. Soc., 119, 1464–1465.
  • David, W. M., Deluca, M., & Kerwin, S. M. (1997). Synthesis of Tetrahydrobis(benzazole) Morpholexins. Abstracts of the 35th National Organic Chemistry Symposium.
  • David, W. M., & Kerwin, S. M. (1997). Complementary Routes to E- and Z-tetrasubstituted ?-alkynylacrylonitriles. Book of Abstracts  213th ACS National Meeting.

1996

  • David, W. M., & Kerwin, S. M. (1996). Aza-Bergman Route to 2,5-didehydropyridines. Book of Abstracts 211th ACS National Meeting.