Faculty Profile for Dr. Shannon E Weigum

profile photo for Dr. Shannon E Weigum
Dr. Shannon E Weigum
Associate Professor — Biology
Program Staff — Center for Innovation + Entrepreneurship
IGRM 5001B
phone: (512) 245-2178

Biography Section

Biography and Education

Dr. Weigum is an interdisciplinary scientist and researcher focused upon the development of optical biosensors and microfluidic devices that can detect and diagnose disease at the point-of-care. Dr. Weigum is currently an Associate Professor in Biology and core faculty for the Materials Science, Engineering and Commercialization Program at Texas State University. She holds a bachelor’s degree from Texas A&M University, a master’s degree from Texas State, and a doctoral degree in Biochemistry from the University of Texas at Austin. She was a postdoctoral fellow in Biomedical Engineering at Rice University before joining the Texas State faculty in 2011. Dr. Weigum has published numerous peer-reviewed manuscripts and poster abstracts, four book chapters, and holds two US patents. Her work has been featured nationally in Popular Science, CNET news and on the cover of the journal Lab-on-a-Chip.

Research Interests

The goal of my research is to design simple, patterned microfluidic devices for high-sensitivity diagnostic assays (whole-cells, DNA, proteins, and viruses) which are rapid, inexpensive, and can be deployed at the point-of-care. The key focus areas for this research include: (1) novel sample preparation methods for concentrating and isolating target pathogens or clinically relevant biomarkers prior to downstream assays; (2) alternative capillary-driven microfluidic substrates, such as paper and; (3) the integration of straightforward colorimetric, optical and spectroscopic detection schemes.

Selected Scholarly/Creative Work

  • Weigum, S. E., & Rohde, R. E. (2021). Nucleic Acid-Based Analytic Methods for Microbial Identification and Characterization. In Bailey & Scott’s Diagnostic Microbiology. St. Louis, Missouri: Elsevier Inc.
  • Weigum, S. E., & Rohde, R. E. (2021). Overview of the Methods and Strategies in Virology. In Bailey & Scott’s Diagnostic Microbiology. St. Louis, Missouri: Elsevier Inc.
  • Weigum, S. E., & Rohde, R. E. (2021). Viruses in Human Disease. In Bailey & Scott’s Diagnostic Microbiology. St. Louis, Missouri: Elsevier Inc.
  • Sousares, M., Partridge, V., Weigum, S., & Du, L. (2017). MicroRNAs in neuroblastoma differentiation and differentiation therapy. Advances in Modern Oncology Research, 3(5), 213. https://doi.org/10.18282/amor.v3.i5.233
  • Rohde, R. E., Weigum, S. E., & McGowin, C. (2017). Nucleic Acid-Based Analytic Methods for Microbial Identification and Characterization. In Bailey & Scott’s Diagnostic Microbiology, 14th ed. Philadelphia, PA: Elsevier Inc.

Selected Awards

  • Award / Honor Nominee: Presidential Award for Service, Texas State University. March 2021
  • Award / Honor Recipient: Presidential Award for Service in College of Science and Engineering, Texas State University. August 2021
  • Award / Honor Recipient: Favorite Professor, Alfred H. Nolle Chapter of the Alpha Chi National College Honor Society. 2016
  • Award / Honor Recipient: Named in at least one student survey as a faculty member that they felt contributed significantly to their success and development throughout their first semester on campus, Texas State University. 2016
  • Award / Honor Recipient: Favorite Professor, Alfred H. Nolle Chapter of the Alpha Chi National College Honor Society. 2015

Selected Grants

  • Weigum, Shannon E (Co-Principal). Aptamer Beacons for Manual and Remote Automated Microbial Detection, NASA SBIR Phase I; Nanohmics, Federal, $149988. (Funded: July 1, 2019 - January 31, 2020). Grant.
  • Weigum, Shannon E. Aptamer-Guided Antibiotic-Loaded Exosomes for Improved Treatment of Bacterial Wound Infections, Nanhomics/Defense Health Agency, Federal, $75000. (Funded: March 1, 2024 - August 30, 2024). Grant.
  • Weigum, Shannon E (Principal). Detecting SARS-CoV-2 in Wastewater Using Molecular Buoys: A New Approach, Texas State University, Institutional (Higher Ed), $5628. (Submitted: October 13, 2020, Funded: January 15, 2021 - December 30, 2022). Grant.
  • Wistey, Mark A, Chen, Yihong (Co-Principal), Weigum, Shannon E, Benavides, Elizabeth Ashley, Ngu, Hee Hiong, Irvin, Jennifer A, Betancourt, Tania, Holtz, Mark W. FEES and Machine Learning for Diagnostics, Texas State University, Texas State University, $10000. (Funded: March 2019 - March 2020). Grant.
  • Weigum, Shannon E (Principal). Targeting Liver Cancer with a Nucleic Acid Aptamer, Texas State University Research Enhancement Program (REP), Texas State University, $8000. (Submitted: October 1, 2016, Funded: January 15, 2017 - December 30, 2017). Grant.

Selected Service Activities

Chair
GSMP Vision 2025 Initiative - Incubator and Accelerator Project
December 2021-Present
Member
Education Workforce Council
August 2021-Present
Organizer
Nina Vaca Innovation and Entrepreneurship Award
March 2021-Present
Member
Texas Global Health Security Consortium Steering Committee
September 2020-Present
Organizer
One Million Cups
September 2020-Present